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Page 1
Targeting the liver clock improves fibrosis by restoring TGF-β signaling.
Crouchet E, Dachraoui M, Jühling F, Roehlen N, Oudot MA, Durand SC, Ponsolles C, Gadenne C, Meiss-Heydmann L, Moehlin J, Martin R, Brignon N, Del Zompo F, Teraoka Y, Aikata H, Abe-Chayama H, Chayama K, Saviano A, Heide D, Onea M, Geyer L, Wolf T, Felli E, Pessaux P, Heikenwälder M, Chambon P, Schuster C, Lupberger J, Mukherji A, Baumert TF. Crouchet E, et al. Among authors: oudot ma. J Hepatol. 2025 Jan;82(1):120-133. doi: 10.1016/j.jhep.2024.07.034. Epub 2024 Aug 22. J Hepatol. 2025. PMID: 39173955 Free PMC article.
Effect of Remifentanil vs Neuromuscular Blockers During Rapid Sequence Intubation on Successful Intubation Without Major Complications Among Patients at Risk of Aspiration: A Randomized Clinical Trial.
Grillot N, Lebuffe G, Huet O, Lasocki S, Pichon X, Oudot M, Bruneau N, David JS, Bouzat P, Jobert A, Tching-Sin M, Feuillet F, Cinotti R, Asehnoune K, Roquilly A; Atlanrea Study GroupSociété Française d’Anesthésie Réanimation (SFAR) Research Network. Grillot N, et al. Among authors: oudot m. JAMA. 2023 Jan 3;329(1):28-38. doi: 10.1001/jama.2022.23550. JAMA. 2023. PMID: 36594947 Free PMC article. Clinical Trial.
Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment.
Roehlen N, Muller M, Nehme Z, Crouchet E, Jühling F, Del Zompo F, Cherradi S, Duong FHT, Almeida N, Saviano A, Fernández-Vaquero M, Riedl T, El Saghire H, Durand SC, Ponsolles C, Oudot MA, Martin R, Brignon N, Felli E, Pessaux P, Lallement A, Davidson I, Bandiera S, Thumann C, Marchand P, Moll S, Nicolay B, Bardeesy N, Hoshida Y, Heikenwälder M, Iacone R, Toso A, Meyer M, Elson G, Schweighoffer T, Teixeira G, Zeisel MB, Laquerriere P, Lupberger J, Schuster C, Mailly L, Baumert TF. Roehlen N, et al. Among authors: oudot ma. J Hepatol. 2023 Feb;78(2):343-355. doi: 10.1016/j.jhep.2022.10.011. Epub 2022 Oct 27. J Hepatol. 2023. PMID: 36309131 Free article.
A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity.
Roehlen N, Saviano A, El Saghire H, Crouchet E, Nehme Z, Del Zompo F, Jühling F, Oudot MA, Durand SC, Duong FHT, Cherradi S, Gonzalez Motos V, Almeida N, Ponsolles C, Heydmann L, Ostyn T, Lallement A, Pessaux P, Felli E, Cavalli A, Sgrignani J, Thumann C, Koutsopoulos O, Fuchs BC, Hoshida Y, Hofmann M, Vyberg M, Viuff BM, Galsgaard ED, Elson G, Toso A, Meyer M, Iacone R, Schweighoffer T, Teixeira G, Moll S, De Vito C, Roskams T, Davidson I, Heide D, Heikenwälder M, Zeisel MB, Lupberger J, Mailly L, Schuster C, Baumert TF. Roehlen N, et al. Among authors: oudot ma. Sci Transl Med. 2022 Dec 21;14(676):eabj4221. doi: 10.1126/scitranslmed.abj4221. Epub 2022 Dec 21. Sci Transl Med. 2022. PMID: 36542691
A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery.
Crouchet E, Bandiera S, Fujiwara N, Li S, El Saghire H, Fernández-Vaquero M, Riedl T, Sun X, Hirschfield H, Jühling F, Zhu S, Roehlen N, Ponsolles C, Heydmann L, Saviano A, Qian T, Venkatesh A, Lupberger J, Verrier ER, Sojoodi M, Oudot MA, Duong FHT, Masia R, Wei L, Thumann C, Durand SC, González-Motos V, Heide D, Hetzer J, Nakagawa S, Ono A, Song WM, Higashi T, Sanchez R, Kim RS, Bian CB, Kiani K, Croonenborghs T, Subramanian A, Chung RT, Straub BK, Schuppan D, Ankavay M, Cocquerel L, Schaeffer E, Goossens N, Koh AP, Mahajan M, Nair VD, Gunasekaran G, Schwartz ME, Bardeesy N, Shalek AK, Rozenblatt-Rosen O, Regev A, Felli E, Pessaux P, Tanabe KK, Heikenwälder M, Schuster C, Pochet N, Zeisel MB, Fuchs BC, Hoshida Y, Baumert TF. Crouchet E, et al. Among authors: oudot ma. Nat Commun. 2021 Sep 17;12(1):5525. doi: 10.1038/s41467-021-25468-9. Nat Commun. 2021. PMID: 34535664 Free PMC article.
An atlas of the human liver diurnal transcriptome and its perturbation by hepatitis C virus infection.
Mukherji A, Jühling F, Simanjuntak Y, Crouchet E, Del Zompo F, Teraoka Y, Haller A, Baltzinger P, Paritala S, Rasha F, Fujiwara N, Gadenne C, Slovic N, Oudot MA, Durand SC, Ponsolles C, Schuster C, Zhuang X, Holmes J, Yeh ML, Abe-Chayama H, Heikenwälder M, Sangiovanni A, Iavarone M, Colombo M, Foung SKH, McKeating JA, Davidson I, Yu ML, Chung RT, Hoshida Y, Chayama K, Lupberger J, Baumert TF. Mukherji A, et al. Among authors: oudot ma. Nat Commun. 2024 Aug 29;15(1):7486. doi: 10.1038/s41467-024-51698-8. Nat Commun. 2024. PMID: 39209804 Free PMC article.
Targeting peroxiredoxin 2 prevents hepatocarcinogenesis in metabolic liver disease models.
Crouchet E, Schaeffer E, Oudot MA, Moehlin J, Gadenne C, Jühling F, El Saghire H, Fujiwara N, Zhu S, Akter Rasha F, Durand SC, Charlot A, Ponsolles C, Martin R, Brignon N, Del Zompo F, Meiss-Heydmann L, Parnot M, Hamdane N, Heide D, Hetzer J, Heikenwälder M, Felli E, Pessaux P, Pochet N, Zoll J, Cunniff B, Hoshida Y, Mailly L, Baumert TF, Schuster C. Crouchet E, et al. Among authors: oudot ma. J Clin Invest. 2025 Sep 11;135(21):e169395. doi: 10.1172/JCI169395. eCollection 2025 Nov 3. J Clin Invest. 2025. PMID: 40932790 Free PMC article.
Protein tyrosine phosphatase delta is a STAT3-phosphatase and suppressor of metabolic liver disease.
Roca Suarez AA, Jühling F, Moehlin J, Mailly L, Virzì A, Brignon N, Durand SC, Oudot MA, Schaeffer E, Martin R, Meiss-Heydmann L, Bach C, Boulahtouf Z, Girard L, Osswald E, Jamey C, Brumaru D, Dali-Youcef N, Mukherji A, Saez-Palma M, Testoni B, Zoulim F, Koneru B, Fujiwara N, Hoshida Y, Felli E, Pessaux P, Tremblay ML, Parent R, Schuster C, Baumert TF, Lupberger J. Roca Suarez AA, et al. Among authors: oudot ma. eGastroenterology. 2025 Jan 27;3(1):e100159. doi: 10.1136/egastro-2024-100159. eCollection 2025. eGastroenterology. 2025. PMID: 40124988 Free PMC article.
Hepatitis B virus-infected hepatocytes promote the secretion of collagen VI to the extracellular matrix.
Virzì A, Boulahtouf Z, Moehlin J, Girard L, Meiss-Heydmann L, Bach C, Gerges E, Durand SC, Oudot MA, Roca Suarez AA, Popp O, Ramberger E, Mertins P, Felli E, Pessaux P, Schuster C, Verrier ER, Baumert TF, Lupberger J. Virzì A, et al. Among authors: oudot ma. Sci Rep. 2025 Jul 10;15(1):24949. doi: 10.1038/s41598-025-09870-7. Sci Rep. 2025. PMID: 40640389 Free PMC article.
A patient-derived HCC spheroid system to model the tumor microenvironment and treatment response.
Crouchet E, Almeida N, Durand SC, Parnot M, Oudot MA, Giannone F, Gadenne C, Roehlen N, Saviano A, Felli E, Pessaux P, Duong HT, Ohdan H, Aikata H, Chayama K, Baumert TF, Schuster C. Crouchet E, et al. Among authors: oudot ma. JHEP Rep. 2024 Oct 28;7(2):101252. doi: 10.1016/j.jhepr.2024.101252. eCollection 2025 Feb. JHEP Rep. 2024. PMID: 39897611 Free PMC article.
25 results