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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 2
1991 1
1993 6
1994 3
1996 1
1998 3
2002 1
2004 1
2006 2
2008 1
2009 1
2010 1
2011 4
2012 6
2013 9
2014 15
2015 16
2016 8
2017 10
2018 3
2019 2
2020 3
2021 1
2022 1
2025 1

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87 results

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Page 1
A comprehensive map of molecular drug targets.
Santos R, Ursu O, Gaulton A, Bento AP, Donadi RS, Bologa CG, Karlsson A, Al-Lazikani B, Hersey A, Oprea TI, Overington JP. Santos R, et al. Among authors: overington jp. Nat Rev Drug Discov. 2017 Jan;16(1):19-34. doi: 10.1038/nrd.2016.230. Epub 2016 Dec 2. Nat Rev Drug Discov. 2017. PMID: 27910877 Free PMC article. Review.
An atlas of genetic influences on human blood metabolites.
Shin SY, Fauman EB, Petersen AK, Krumsiek J, Santos R, Huang J, Arnold M, Erte I, Forgetta V, Yang TP, Walter K, Menni C, Chen L, Vasquez L, Valdes AM, Hyde CL, Wang V, Ziemek D, Roberts P, Xi L, Grundberg E; Multiple Tissue Human Expression Resource (MuTHER) Consortium; Waldenberger M, Richards JB, Mohney RP, Milburn MV, John SL, Trimmer J, Theis FJ, Overington JP, Suhre K, Brosnan MJ, Gieger C, Kastenmüller G, Spector TD, Soranzo N. Shin SY, et al. Among authors: overington jp. Nat Genet. 2014 Jun;46(6):543-550. doi: 10.1038/ng.2982. Epub 2014 May 11. Nat Genet. 2014. PMID: 24816252 Free PMC article.
How many drug targets are there?
Overington JP, Al-Lazikani B, Hopkins AL. Overington JP, et al. Nat Rev Drug Discov. 2006 Dec;5(12):993-6. doi: 10.1038/nrd2199. Nat Rev Drug Discov. 2006. PMID: 17139284 Review.
Setting Our Sights on Infectious Diseases.
De Rycker M, Horn D, Aldridge B, Amewu RK, Barry CE 3rd, Buckner FS, Cook S, Ferguson MAJ, Gobeau N, Herrmann J, Herrling P, Hope W, Keiser J, Lafuente-Monasterio MJ, Leeson PD, Leroy D, Manjunatha UH, McCarthy J, Miles TJ, Mizrahi V, Moshynets O, Niles J, Overington JP, Pottage J, Rao SPS, Read KD, Ribeiro I, Silver LL, Southern J, Spangenberg T, Sundar S, Taylor C, Van Voorhis W, White NJ, Wyllie S, Wyatt PG, Gilbert IH. De Rycker M, et al. Among authors: overington jp. ACS Infect Dis. 2020 Jan 10;6(1):3-13. doi: 10.1021/acsinfecdis.9b00371. Epub 2019 Dec 6. ACS Infect Dis. 2020. PMID: 31808676 Free PMC article.
The ChEMBL database: a taster for medicinal chemists.
Papadatos G, Overington JP. Papadatos G, et al. Among authors: overington jp. Future Med Chem. 2014 Mar;6(4):361-4. doi: 10.4155/fmc.14.8. Future Med Chem. 2014. PMID: 24635517 No abstract available.
Structural and Functional View of Polypharmacology.
Moya-García A, Adeyelu T, Kruger FA, Dawson NL, Lees JG, Overington JP, Orengo C, Ranea JAG. Moya-García A, et al. Among authors: overington jp. Sci Rep. 2017 Aug 31;7(1):10102. doi: 10.1038/s41598-017-10012-x. Sci Rep. 2017. PMID: 28860623 Free PMC article.
Unexplored therapeutic opportunities in the human genome.
Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G. Oprea TI, et al. Among authors: overington jp. Nat Rev Drug Discov. 2018 May;17(5):317-332. doi: 10.1038/nrd.2018.14. Epub 2018 Mar 23. Nat Rev Drug Discov. 2018. PMID: 29472638 Free PMC article. Review.
The ChEMBL database in 2017.
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. Gaulton A, et al. Among authors: overington jp. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954. doi: 10.1093/nar/gkw1074. Epub 2016 Nov 28. Nucleic Acids Res. 2017. PMID: 27899562 Free PMC article.
87 results