A novel zinc-binding motif found in two ubiquitous deaminase families
- PMID: 8061614
- PMCID: PMC2142716
- DOI: 10.1002/pro.5560030515
A novel zinc-binding motif found in two ubiquitous deaminase families
Abstract
Two families of deaminases, one specific for cytidine, the other for deoxycytidylate, are shown to possess a novel zinc-binding motif, here designated ZBS. We have (1) identified the protein members of these 2 families, (2) carried out sequence analyses that allow specification of this zinc-binding motif, and (3) determined signature sequences that will allow identification of additional members of these families as their sequences become available.
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