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Dual functionality of β-tryptase protomers as both proteases and cofactors in the active tetramer.
J Biol Chem. 2018 Jun 22;293(25):9614-9628. doi: 10.1074/jbc.M117.812016. Epub 2018 Apr 16.
J Biol Chem. 2018.
PMID: 29661938
Free PMC article.
Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.
Pereira PJ, Bergner A, Macedo-Ribeiro S, Huber R, Matschiner G, Fritz H, Sommerhoff CP, Bode W.
Pereira PJ, et al.
Nature. 1998 Mar 19;392(6673):306-11. doi: 10.1038/32703.
Nature. 1998.
PMID: 9521329
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