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Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice.
J Biol Chem. 2017 Mar 3;292(9):3900-3908. doi: 10.1074/jbc.M116.767749. Epub 2017 Jan 11.
J Biol Chem. 2017.
PMID: 28077575
Free PMC article.
Molecular basis for immune complex recognition: a comparison of Fc-receptor structures.
Sondermann P, Kaiser J, Jacob U.
Sondermann P, et al.
J Mol Biol. 2001 Jun 8;309(3):737-49. doi: 10.1006/jmbi.2001.4670.
J Mol Biol. 2001.
PMID: 11397093
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A single amino acid distorts the Fc γ receptor IIIb/CD16b structure upon binding immunoglobulin G1 and reduces affinity relative to CD16a.
Roberts JT, Barb AW.
Roberts JT, et al.
J Biol Chem. 2018 Dec 21;293(51):19899-19908. doi: 10.1074/jbc.RA118.005273. Epub 2018 Oct 25.
J Biol Chem. 2018.
PMID: 30361439
Free PMC article.
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