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Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4).
J Biol Chem. 2019 Mar 22;294(12):4511-4519. doi: 10.1074/jbc.RA118.005428. Epub 2019 Jan 24.
J Biol Chem. 2019.
PMID: 30679311
Free PMC article.
High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design.
Schulze-Gahmen U, De Bondt HL, Kim SH.
Schulze-Gahmen U, et al.
J Med Chem. 1996 Nov 8;39(23):4540-6. doi: 10.1021/jm960402a.
J Med Chem. 1996.
PMID: 8917641
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