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BLVRB redox mutation defines heme degradation in a metabolic pathway of enhanced thrombopoiesis in humans.
Blood. 2016 Aug 4;128(5):699-709. doi: 10.1182/blood-2016-02-696997. Epub 2016 May 16.
Blood. 2016.
PMID: 27207795
Free PMC article.
Structure of human biliverdin IXbeta reductase, an early fetal bilirubin IXbeta producing enzyme.
Pereira PJ, Macedo-Ribeiro S, Párraga A, Pérez-Luque R, Cunningham O, Darcy K, Mantle TJ, Coll M.
Pereira PJ, et al.
Nat Struct Biol. 2001 Mar;8(3):215-20. doi: 10.1038/84948.
Nat Struct Biol. 2001.
PMID: 11224564
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In silico and crystallographic studies identify key structural features of biliverdin IXβ reductase inhibitors having nanomolar potency.
Nesbitt NM, Zheng X, Li Z, Manso JA, Yen WY, Malone LE, Ripoll-Rozada J, Pereira PJB, Mantle TJ, Wang J, Bahou WF.
Nesbitt NM, et al.
J Biol Chem. 2018 Apr 13;293(15):5431-5446. doi: 10.1074/jbc.RA118.001803. Epub 2018 Feb 27.
J Biol Chem. 2018.
PMID: 29487133
Free PMC article.
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