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Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System.
J Biol Chem. 2016 Mar 25;291(13):6723-31. doi: 10.1074/jbc.R115.692665. Epub 2016 Feb 5.
J Biol Chem. 2016.
PMID: 26851277
Free PMC article.
Review.
Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase.
French ME, Klosowiak JL, Aslanian A, Reed SI, Yates JR 3rd, Hunter T.
French ME, et al.
J Biol Chem. 2017 Jun 23;292(25):10398-10413. doi: 10.1074/jbc.M117.789479. Epub 2017 May 1.
J Biol Chem. 2017.
PMID: 28461335
Free PMC article.
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Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase.
Verdecia MA, Joazeiro CA, Wells NJ, Ferrer JL, Bowman ME, Hunter T, Noel JP.
Verdecia MA, et al.
Mol Cell. 2003 Jan;11(1):249-59. doi: 10.1016/s1097-2765(02)00774-8.
Mol Cell. 2003.
PMID: 12535537
Free article.
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