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Allosteric inhibition of protein tyrosine phosphatase 1B.
Nat Struct Mol Biol. 2004 Aug;11(8):730-7. doi: 10.1038/nsmb803. Epub 2004 Jul 18.
Nat Struct Mol Biol. 2004.
PMID: 15258570
Discovery of a potent, selective protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategy.
Szczepankiewicz BG, Liu G, Hajduk PJ, Abad-Zapatero C, Pei Z, Xin Z, Lubben TH, Trevillyan JM, Stashko MA, Ballaron SJ, Liang H, Huang F, Hutchins CW, Fesik SW, Jirousek MR.
Szczepankiewicz BG, et al.
J Am Chem Soc. 2003 Apr 9;125(14):4087-96. doi: 10.1021/ja0296733.
J Am Chem Soc. 2003.
PMID: 12670229
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