PDB/1P8J[Secondary Source ID] - Search Results

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Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza.

Ohno A, Maita N, Tabata T, Nagano H, Arita K, Ariyoshi M, Uchida T, Nakao R, Ulla A, Sugiura K, Kishimoto K, Teshima-Kondo S, Okumura Y, Nikawa T. Ohno A, et al. Life Sci Alliance. 2021 Apr 5;4(6):e202000849. doi: 10.26508/lsa.202000849. Print 2021 Jun. Life Sci Alliance. 2021. PMID: 33820827 Free PMC article.

The crystal structure of the proprotein processing proteinase furin explains its stringent specificity.

Henrich S, Cameron A, Bourenkov GP, Kiefersauer R, Huber R, Lindberg I, Bode W, Than ME. Henrich S, et al. Nat Struct Biol. 2003 Jul;10(7):520-6. doi: 10.1038/nsb941. Nat Struct Biol. 2003. PMID: 12794637

The Multi-Leu peptide inhibitor discriminates between PACE4 and furin and exhibits antiproliferative effects on prostate cancer cells.

Levesque C, Fugère M, Kwiatkowska A, Couture F, Desjardins R, Routhier S, Moussette P, Prahl A, Lammek B, Appel JR, Houghten RA, D'Anjou F, Dory YL, Neugebauer W, Day R. Levesque C, et al. J Med Chem. 2012 Dec 13;55(23):10501-11. doi: 10.1021/jm3011178. Epub 2012 Nov 14. J Med Chem. 2012. PMID: 23126600 Free PMC article.

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