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Reversible covalent c-Jun N-terminal kinase inhibitors targeting a specific cysteine by precision-guided Michael-acceptor warheads.
Bálint D, Póti ÁL, Alexa A, Sok P, Albert K, Torda L, Földesi-Nagy D, Csókás D, Turczel G, Imre T, Szarka E, Fekete F, Bento I, Bojtár M, Palkó R, Szabó P, Monostory K, Pápai I, Soós T, Reményi A. Bálint D, et al. Nat Commun. 2024 Oct 4;15(1):8606. doi: 10.1038/s41467-024-52573-2. Nat Commun. 2024. PMID: 39366946 Free PMC article.