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Active-site differences between substrate-free and ritonavir-bound cytochrome P450 (CYP) 3A5 reveal plasticity differences between CYP3A5 and CYP3A4.
J Biol Chem. 2019 May 17;294(20):8015-8022. doi: 10.1074/jbc.RA119.007928. Epub 2019 Mar 29.
J Biol Chem. 2019.
PMID: 30926609
Free PMC article.
Structural basis for ligand promiscuity in cytochrome P450 3A4.
Ekroos M, Sjögren T.
Ekroos M, et al.
Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13682-7. doi: 10.1073/pnas.0603236103. Epub 2006 Sep 5.
Proc Natl Acad Sci U S A. 2006.
PMID: 16954191
Free PMC article.
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