PDB/2JIU[Secondary Source ID] - Search Results

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The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP.

Yun CH, Mengwasser KE, Toms AV, Woo MS, Greulich H, Wong KK, Meyerson M, Eck MJ. Yun CH, et al. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2070-5. doi: 10.1073/pnas.0709662105. Epub 2008 Jan 28. Proc Natl Acad Sci U S A. 2008. PMID: 18227510 Free PMC article.

Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib.

Kancha RK, von Bubnoff N, Bartosch N, Peschel C, Engh RA, Duyster J. Kancha RK, et al. PLoS One. 2011;6(10):e26760. doi: 10.1371/journal.pone.0026760. Epub 2011 Oct 28. PLoS One. 2011. PMID: 22046346 Free PMC article.

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