PDB/2KMS[Secondary Source ID] - Search Results

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2009	1
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The solution structure of the complement deregulator FHR5 reveals a compact dimer and provides new insights into CFHR5 nephropathy.

Kadkhodayi-Kholghi N, Bhatt JS, Gor J, McDermott LC, Gale DP, Perkins SJ. Kadkhodayi-Kholghi N, et al. J Biol Chem. 2020 Nov 27;295(48):16342-16358. doi: 10.1074/jbc.RA120.015132. Epub 2020 Sep 14. J Biol Chem. 2020. PMID: 32928961 Free PMC article.

Two distinct conformations of factor H regulate discrete complement-binding functions in the fluid phase and at cell surfaces.

Osborne AJ, Nan R, Miller A, Bhatt JS, Gor J, Perkins SJ. Osborne AJ, et al. J Biol Chem. 2018 Nov 2;293(44):17166-17187. doi: 10.1074/jbc.RA118.004767. Epub 2018 Sep 14. J Biol Chem. 2018. PMID: 30217822 Free PMC article.

The central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP module.

Schmidt CQ, Herbert AP, Mertens HD, Guariento M, Soares DC, Uhrin D, Rowe AJ, Svergun DI, Barlow PN. Schmidt CQ, et al. J Mol Biol. 2010 Jan 8;395(1):105-22. doi: 10.1016/j.jmb.2009.10.010. Epub 2009 Oct 14. J Mol Biol. 2010. PMID: 19835885 Free PMC article.

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