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Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling.
Nature. 2010 Jun 17;465(7300):885-90. doi: 10.1038/nature09121. Epub 2010 May 19.
Nature. 2010.
PMID: 20485341
Free PMC article.
Mechanism of dysfunction of human variants of the IRAK4 kinase and a role for its kinase activity in interleukin-1 receptor signaling.
De S, Karim F, Kiessu E, Cushing L, Lin LL, Ghandil P, Hoarau C, Casanova JL, Puel A, Rao VR.
De S, et al.
J Biol Chem. 2018 Sep 28;293(39):15208-15220. doi: 10.1074/jbc.RA118.003831. Epub 2018 Aug 16.
J Biol Chem. 2018.
PMID: 30115681
Free PMC article.
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A highly selective inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase.
Scarneo SA, Hughes PF, Yang KW, Carlson DA, Gurbani D, Westover KD, Haystead TAJ.
Scarneo SA, et al.
J Biol Chem. 2020 Feb 7;295(6):1565-1574. doi: 10.1074/jbc.RA119.011857. Epub 2019 Dec 30.
J Biol Chem. 2020.
PMID: 31914413
Free PMC article.
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