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Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples.
J Biol Chem. 2019 Nov 1;294(44):16451-16464. doi: 10.1074/jbc.RA119.009688. Epub 2019 Sep 19.
J Biol Chem. 2019.
PMID: 31537646
Free PMC article.
Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Sawaya MR, Sambashivan S, Nelson R, Ivanova MI, Sievers SA, Apostol MI, Thompson MJ, Balbirnie M, Wiltzius JJ, McFarlane HT, Madsen AØ, Riekel C, Eisenberg D.
Sawaya MR, et al.
Nature. 2007 May 24;447(7143):453-7. doi: 10.1038/nature05695. Epub 2007 Apr 29.
Nature. 2007.
PMID: 17468747
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