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Crystallographic trapping in the rebeccamycin biosynthetic enzyme RebC.
Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15311-6. doi: 10.1073/pnas.0707190104. Epub 2007 Sep 14.
Proc Natl Acad Sci U S A. 2007.
PMID: 17873060
Free PMC article.
The FAD cofactor of RebC shifts to an IN conformation upon flavin reduction.
Ryan KS, Chakraborty S, Howard-Jones AR, Walsh CT, Ballou DP, Drennan CL.
Ryan KS, et al.
Biochemistry. 2008 Dec 23;47(51):13506-13. doi: 10.1021/bi801229w.
Biochemistry. 2008.
PMID: 19035832
Free PMC article.
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Structural analyses of the Group A flavin-dependent monooxygenase PieE reveal a sliding FAD cofactor conformation bridging OUT and IN conformations.
Manenda MS, Picard MÈ, Zhang L, Cyr N, Zhu X, Barma J, Pascal JM, Couture M, Zhang C, Shi R.
Manenda MS, et al.
J Biol Chem. 2020 Apr 3;295(14):4709-4722. doi: 10.1074/jbc.RA119.011212. Epub 2020 Feb 28.
J Biol Chem. 2020.
PMID: 32111738
Free PMC article.
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