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Transition-state destabilization reveals how human DNA polymerase β proceeds across the chemically unstable lesion N7-methylguanine.
Nucleic Acids Res. 2014 Jul;42(13):8755-66. doi: 10.1093/nar/gku554. Epub 2014 Jun 25.
Nucleic Acids Res. 2014.
PMID: 24966350
Free PMC article.
Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation.
Batra VK, Beard WA, Shock DD, Pedersen LC, Wilson SH.
Batra VK, et al.
Mol Cell. 2008 May 9;30(3):315-24. doi: 10.1016/j.molcel.2008.02.025.
Mol Cell. 2008.
PMID: 18471977
Free PMC article.
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