PDB/3C98[Secondary Source ID] - Search Results

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Hemophagocytic lymphohistiocytosis caused by dominant-negative mutations in STXBP2 that inhibit SNARE-mediated membrane fusion.

Spessott WA, Sanmillan ML, McCormick ME, Patel N, Villanueva J, Zhang K, Nichols KE, Giraudo CG. Spessott WA, et al. Blood. 2015 Mar 5;125(10):1566-77. doi: 10.1182/blood-2014-11-610816. Epub 2015 Jan 6. Blood. 2015. PMID: 25564401 Free PMC article.

Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide.

Burkhardt P, Hattendorf DA, Weis WI, Fasshauer D. Burkhardt P, et al. EMBO J. 2008 Apr 9;27(7):923-33. doi: 10.1038/emboj.2008.37. Epub 2008 Mar 13. EMBO J. 2008. PMID: 18337752 Free PMC article.

Evidence for a conserved inhibitory binding mode between the membrane fusion assembly factors Munc18 and syntaxin in animals.

Morey C, Kienle CN, Klöpper TH, Burkhardt P, Fasshauer D. Morey C, et al. J Biol Chem. 2017 Dec 15;292(50):20449-20460. doi: 10.1074/jbc.M117.811182. Epub 2017 Oct 18. J Biol Chem. 2017. PMID: 29046354 Free PMC article.

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