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Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases.
J Biol Chem. 2017 Sep 22;292(38):15598-15610. doi: 10.1074/jbc.M117.790865. Epub 2017 Jul 18.
J Biol Chem. 2017.
PMID: 28726643
Free PMC article.
Crystal structure of ADP-dependent glucokinase from Methanocaldococcus jannaschii in complex with 5-iodotubercidin reveals phosphoryl transfer mechanism.
Tokarz P, Wiśniewska M, Kamiński MM, Dubin G, Grudnik P.
Tokarz P, et al.
Protein Sci. 2018 Mar;27(3):790-797. doi: 10.1002/pro.3377. Epub 2018 Feb 2.
Protein Sci. 2018.
PMID: 29352744
Free PMC article.
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ADP-dependent 6-phosphofructokinase from Pyrococcus horikoshii OT3: structure determination and biochemical characterization of PH1645.
Currie MA, Merino F, Skarina T, Wong AH, Singer A, Brown G, Savchenko A, Caniuguir A, Guixé V, Yakunin AF, Jia Z.
Currie MA, et al.
J Biol Chem. 2009 Aug 21;284(34):22664-71. doi: 10.1074/jbc.M109.012401. Epub 2009 Jun 24.
J Biol Chem. 2009.
PMID: 19553681
Free PMC article.
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