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Stabilization of Nucleotide Binding Domain Dimers Rescues ABCC6 Mutants Associated with Pseudoxanthoma Elasticum.
J Biol Chem. 2017 Feb 3;292(5):1559-1572. doi: 10.1074/jbc.M116.759811. Epub 2016 Dec 19.
J Biol Chem. 2017.
PMID: 27994049
Free PMC article.
Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations.
Vernon RM, Chong PA, Lin H, Yang Z, Zhou Q, Aleksandrov AA, Dawson JE, Riordan JR, Brouillette CG, Thibodeau PH, Forman-Kay JD.
Vernon RM, et al.
J Biol Chem. 2017 Aug 25;292(34):14147-14164. doi: 10.1074/jbc.M116.772335. Epub 2017 Jun 27.
J Biol Chem. 2017.
PMID: 28655774
Free PMC article.
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Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator.
Wang C, Aleksandrov AA, Yang Z, Forouhar F, Proctor EA, Kota P, An J, Kaplan A, Khazanov N, Boël G, Stockwell BR, Senderowitz H, Dokholyan NV, Riordan JR, Brouillette CG, Hunt JF.
Wang C, et al.
J Biol Chem. 2018 Nov 16;293(46):17685-17704. doi: 10.1074/jbc.RA117.000819. Epub 2018 Jun 14.
J Biol Chem. 2018.
PMID: 29903914
Free PMC article.
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