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Isomerization as the secret Achilles' heel of long-lived proteins.
J Biol Chem. 2019 May 10;294(19):7556-7557. doi: 10.1074/jbc.H119.008716.
J Biol Chem. 2019.
PMID: 31076522
Free PMC article.
Structural model of dodecameric heat-shock protein Hsp21: Flexible N-terminal arms interact with client proteins while C-terminal tails maintain the dodecamer and chaperone activity.
Rutsdottir G, Härmark J, Weide Y, Hebert H, Rasmussen MI, Wernersson S, Respondek M, Akke M, Højrup P, Koeck PJB, Söderberg CAG, Emanuelsson C.
Rutsdottir G, et al.
J Biol Chem. 2017 May 12;292(19):8103-8121. doi: 10.1074/jbc.M116.766816. Epub 2017 Mar 21.
J Biol Chem. 2017.
PMID: 28325834
Free PMC article.
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