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Binding of a physiological substrate causes large-scale conformational reorganization in cytochrome P450 51.
J Biol Chem. 2018 Dec 14;293(50):19344-19353. doi: 10.1074/jbc.RA118.005850. Epub 2018 Oct 16.
J Biol Chem. 2018.
PMID: 30327430
Free PMC article.
Comparison of intrinsic dynamics of cytochrome p450 proteins using normal mode analysis.
Dorner ME, McMunn RD, Bartholow TG, Calhoon BE, Conlon MR, Dulli JM, Fehling SC, Fisher CR, Hodgson SW, Keenan SW, Kruger AN, Mabin JW, Mazula DL, Monte CA, Olthafer A, Sexton AE, Soderholm BR, Strom AM, Hati S.
Dorner ME, et al.
Protein Sci. 2015 Sep;24(9):1495-507. doi: 10.1002/pro.2737. Epub 2015 Jul 16.
Protein Sci. 2015.
PMID: 26130403
Free PMC article.
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Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1.
Mast N, Annalora AJ, Lodowski DT, Palczewski K, Stout CD, Pikuleva IA.
Mast N, et al.
J Biol Chem. 2011 Feb 18;286(7):5607-13. doi: 10.1074/jbc.M110.188433. Epub 2010 Dec 15.
J Biol Chem. 2011.
PMID: 21159775
Free PMC article.
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