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Analysis of β-lactone formation by clinically observed carbapenemases informs on a novel antibiotic resistance mechanism.
J Biol Chem. 2020 Dec 4;295(49):16604-16613. doi: 10.1074/jbc.RA120.014607. Epub 2020 Sep 22.
J Biol Chem. 2020.
PMID: 32963107
Free PMC article.
Structures of the class D carbapenemase OXA-24 from Acinetobacter baumannii in complex with doripenem.
Schneider KD, Ortega CJ, Renck NA, Bonomo RA, Powers RA, Leonard DA.
Schneider KD, et al.
J Mol Biol. 2011 Mar 4;406(4):583-94. doi: 10.1016/j.jmb.2010.12.042. Epub 2011 Jan 6.
J Mol Biol. 2011.
PMID: 21215758
Free PMC article.
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Common clinical substitutions enhance the carbapenemase activity of OXA-51-like class D β-lactamases from Acinetobacter spp.
Mitchell JM, Leonard DA.
Mitchell JM, et al.
Antimicrob Agents Chemother. 2014 Nov;58(11):7015-6. doi: 10.1128/AAC.03651-14. Epub 2014 Aug 25.
Antimicrob Agents Chemother. 2014.
PMID: 25155607
Free PMC article.
No abstract available.
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