PDB/3Q75[Secondary Source ID] - Search Results

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Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design.

Mabanglo MF, Hast MA, Lubock NB, Hellinga HW, Beese LS. Mabanglo MF, et al. Protein Sci. 2014 Mar;23(3):289-301. doi: 10.1002/pro.2411. Epub 2014 Jan 31. Protein Sci. 2014. PMID: 24347326 Free PMC article.

Structures of Cryptococcus neoformans protein farnesyltransferase reveal strategies for developing inhibitors that target fungal pathogens.

Hast MA, Nichols CB, Armstrong SM, Kelly SM, Hellinga HW, Alspaugh JA, Beese LS. Hast MA, et al. J Biol Chem. 2011 Oct 7;286(40):35149-62. doi: 10.1074/jbc.M111.250506. Epub 2011 Aug 4. J Biol Chem. 2011. PMID: 21816822 Free PMC article.

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