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Molecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitors.
Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18281-9. doi: 10.1073/pnas.1207759109. Epub 2012 Sep 17.
Proc Natl Acad Sci U S A. 2012.
PMID: 22988103
Free PMC article.
Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation.
Johnson E, McTigue M, Gallego RA, Johnson TW, Timofeevski S, Maestre M, Fisher TS, Kania R, Sawasdikosol S, Burakoff S, Cronin CN.
Johnson E, et al.
J Biol Chem. 2019 Jun 7;294(23):9029-9036. doi: 10.1074/jbc.AC119.007466. Epub 2019 Apr 24.
J Biol Chem. 2019.
PMID: 31018963
Free PMC article.
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