PDB/4B2R[Secondary Source ID] - Search Results

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The solution structure of the complement deregulator FHR5 reveals a compact dimer and provides new insights into CFHR5 nephropathy.

Kadkhodayi-Kholghi N, Bhatt JS, Gor J, McDermott LC, Gale DP, Perkins SJ. Kadkhodayi-Kholghi N, et al. J Biol Chem. 2020 Nov 27;295(48):16342-16358. doi: 10.1074/jbc.RA120.015132. Epub 2020 Sep 14. J Biol Chem. 2020. PMID: 32928961 Free PMC article.

Solution structure of CCP modules 10-12 illuminates functional architecture of the complement regulator, factor H.

Makou E, Mertens HD, Maciejewski M, Soares DC, Matis I, Schmidt CQ, Herbert AP, Svergun DI, Barlow PN. Makou E, et al. J Mol Biol. 2012 Dec 14;424(5):295-312. doi: 10.1016/j.jmb.2012.09.013. Epub 2012 Sep 25. J Mol Biol. 2012. PMID: 23017427 Free PMC article.

Two distinct conformations of factor H regulate discrete complement-binding functions in the fluid phase and at cell surfaces.

Osborne AJ, Nan R, Miller A, Bhatt JS, Gor J, Perkins SJ. Osborne AJ, et al. J Biol Chem. 2018 Nov 2;293(44):17166-17187. doi: 10.1074/jbc.RA118.004767. Epub 2018 Sep 14. J Biol Chem. 2018. PMID: 30217822 Free PMC article.

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