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Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13374-9. doi: 10.1073/pnas.1301726110. Epub 2013 Jul 29.
Proc Natl Acad Sci U S A. 2013.
PMID: 23898196
Free PMC article.
Electrostatic repulsion causes anticooperative DNA binding between tumor suppressor ETS transcription factors and JUN-FOS at composite DNA sites.
Madison BJ, Clark KA, Bhachech N, Hollenhorst PC, Graves BJ, Currie SL.
Madison BJ, et al.
J Biol Chem. 2018 Nov 30;293(48):18624-18635. doi: 10.1074/jbc.RA118.003352. Epub 2018 Oct 12.
J Biol Chem. 2018.
PMID: 30315111
Free PMC article.
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