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mTOR kinase structure, mechanism and regulation.
Nature. 2013 May 9;497(7448):217-23. doi: 10.1038/nature12122. Epub 2013 May 1.
Nature. 2013.
PMID: 23636326
Free PMC article.
Activation of Tel1ATM kinase requires Rad50 ATPase and long nucleosome-free DNA but no DNA ends.
Hailemariam S, Kumar S, Burgers PM.
Hailemariam S, et al.
J Biol Chem. 2019 Jun 28;294(26):10120-10130. doi: 10.1074/jbc.RA119.008410. Epub 2019 May 9.
J Biol Chem. 2019.
PMID: 31073030
Free PMC article.
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The Dimeric Architecture of Checkpoint Kinases Mec1ATR and Tel1ATM Reveal a Common Structural Organization.
Sawicka M, Wanrooij PH, Darbari VC, Tannous E, Hailemariam S, Bose D, Makarova AV, Burgers PM, Zhang X.
Sawicka M, et al.
J Biol Chem. 2016 Jun 24;291(26):13436-47. doi: 10.1074/jbc.M115.708263. Epub 2016 Apr 28.
J Biol Chem. 2016.
PMID: 27129217
Free PMC article.
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