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Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING.
Mol Cell. 2013 Jul 25;51(2):226-35. doi: 10.1016/j.molcel.2013.05.022. Epub 2013 Jun 6.
Mol Cell. 2013.
PMID: 23747010
Free PMC article.
Crystal structures of porcine STINGCBD-CDN complexes reveal the mechanism of ligand recognition and discrimination of STING proteins.
Cong X, Yuan Z, Du Y, Wu B, Lu D, Wu X, Zhang Y, Li F, Wei B, Li J, Wu J, Xu S, Wang J, Qi J, Shang G, Gu L.
Cong X, et al.
J Biol Chem. 2019 Jul 26;294(30):11420-11432. doi: 10.1074/jbc.RA119.007367. Epub 2019 Jun 5.
J Biol Chem. 2019.
PMID: 31167783
Free PMC article.
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