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Identification of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 that are efficacious in both chemical and surgical models of osteoarthritis.
J Med Chem. 2014 Dec 26;57(24):10476-85. doi: 10.1021/jm501522n. Epub 2014 Dec 5.
J Med Chem. 2014.
PMID: 25415648
FtsZ protofilaments use a hinge-opening mechanism for constrictive force generation.
Li Y, Hsin J, Zhao L, Cheng Y, Shang W, Huang KC, Wang HW, Ye S.
Li Y, et al.
Science. 2013 Jul 26;341(6144):392-5. doi: 10.1126/science.1239248.
Science. 2013.
PMID: 23888039
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