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A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance.
Life Sci Alliance. 2023 Aug 17;6(11):e202302058. doi: 10.26508/lsa.202302058. Print 2023 Nov.
Life Sci Alliance. 2023.
PMID: 37591722
Free PMC article.
Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Bhabha G, Ekiert DC, Jennewein M, Zmasek CM, Tuttle LM, Kroon G, Dyson HJ, Godzik A, Wilson IA, Wright PE.
Bhabha G, et al.
Nat Struct Mol Biol. 2013 Nov;20(11):1243-9. doi: 10.1038/nsmb.2676. Epub 2013 Sep 29.
Nat Struct Mol Biol. 2013.
PMID: 24077226
Free PMC article.
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