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Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange.
Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3401-6. doi: 10.1073/pnas.1315798111. Epub 2014 Feb 18.
Proc Natl Acad Sci U S A. 2014.
PMID: 24550516
Free PMC article.
The Function of Embryonic Stem Cell-expressed RAS (E-RAS), a Unique RAS Family Member, Correlates with Its Additional Motifs and Its Structural Properties.
Nakhaei-Rad S, Nakhaeizadeh H, Kordes C, Cirstea IC, Schmick M, Dvorsky R, Bastiaens PIH, Häussinger D, Ahmadian MR.
Nakhaei-Rad S, et al.
J Biol Chem. 2015 Jun 19;290(25):15892-15903. doi: 10.1074/jbc.M115.640607. Epub 2015 May 4.
J Biol Chem. 2015.
PMID: 25940089
Free PMC article.
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