PDB/4OBE[Secondary Source ID] - Search Results

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Exceptionally high-affinity Ras binders that remodel its effector domain.

McGee JH, Shim SY, Lee SJ, Swanson PK, Jiang SY, Durney MA, Verdine GL. McGee JH, et al. J Biol Chem. 2018 Mar 2;293(9):3265-3280. doi: 10.1074/jbc.M117.816348. Epub 2017 Dec 27. J Biol Chem. 2018. PMID: 29282294 Free PMC article.

Structural basis of the atypical activation mechanism of KRAS^V14I.

Bera AK, Lu J, Wales TE, Gondi S, Gurbani D, Nelson A, Engen JR, Westover KD. Bera AK, et al. J Biol Chem. 2019 Sep 20;294(38):13964-13972. doi: 10.1074/jbc.RA119.009131. Epub 2019 Jul 24. J Biol Chem. 2019. PMID: 31341022 Free PMC article.

In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C.

Hunter JC, Gurbani D, Ficarro SB, Carrasco MA, Lim SM, Choi HG, Xie T, Marto JA, Chen Z, Gray NS, Westover KD. Hunter JC, et al. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8895-900. doi: 10.1073/pnas.1404639111. Epub 2014 Jun 2. Proc Natl Acad Sci U S A. 2014. PMID: 24889603 Free PMC article.

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