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Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide.
Nature. 2015 Jan 29;517(7536):635-9. doi: 10.1038/nature13886. Epub 2014 Nov 17.
Nature. 2015.
PMID: 25409153
Free PMC article.
Molecular and structural characterization of oxidized ribonucleotide insertion into DNA by human DNA polymerase β.
Smith MR, Alnajjar KS, Hoitsma NM, Sweasy JB, Freudenthal BD.
Smith MR, et al.
J Biol Chem. 2020 Feb 7;295(6):1613-1622. doi: 10.1074/jbc.RA119.011569. Epub 2019 Dec 31.
J Biol Chem. 2020.
PMID: 31892517
Free PMC article.
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Molecular basis for the faithful replication of 5-methylcytosine and its oxidized forms by DNA polymerase β.
Howard MJ, Foley KG, Shock DD, Batra VK, Wilson SH.
Howard MJ, et al.
J Biol Chem. 2019 May 3;294(18):7194-7201. doi: 10.1074/jbc.RA118.006809. Epub 2019 Mar 18.
J Biol Chem. 2019.
PMID: 30885943
Free PMC article.
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