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Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors.
Structure. 2015 Jul 7;23(7):1271-82. doi: 10.1016/j.str.2015.04.016. Epub 2015 May 28.
Structure. 2015.
PMID: 26027733
Free article.
Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses.
Macháčková K, Mlčochová K, Potalitsyn P, Hanková K, Socha O, Buděšínský M, Muždalo A, Lepšík M, Černeková M, Radosavljević J, Fábry M, Mitrová K, Chrudinová M, Lin J, Yurenko Y, Hobza P, Selicharová I, Žáková L, Jiráček J.
Macháčková K, et al.
J Biol Chem. 2019 Nov 15;294(46):17371-17382. doi: 10.1074/jbc.RA119.010072. Epub 2019 Sep 26.
J Biol Chem. 2019.
PMID: 31558604
Free PMC article.
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Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
Hexnerová R, Křížková K, Fábry M, Sieglová I, Kedrová K, Collinsová M, Ullrichová P, Srb P, Williams C, Crump MP, Tošner Z, Jiráček J, Veverka V, Žáková L.
Hexnerová R, et al.
J Biol Chem. 2016 Sep 30;291(40):21234-21245. doi: 10.1074/jbc.M116.741041. Epub 2016 Aug 10.
J Biol Chem. 2016.
PMID: 27510031
Free PMC article.
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