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The Bateman domain of IMP dehydrogenase is a binding target for dinucleoside polyphosphates.
J Biol Chem. 2019 Oct 4;294(40):14768-14775. doi: 10.1074/jbc.AC119.010055. Epub 2019 Aug 15.
J Biol Chem. 2019.
PMID: 31416831
Free PMC article.
Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases.
Buey RM, Ledesma-Amaro R, Velázquez-Campoy A, Balsera M, Chagoyen M, de Pereda JM, Revuelta JL.
Buey RM, et al.
Nat Commun. 2015 Nov 12;6:8923. doi: 10.1038/ncomms9923.
Nat Commun. 2015.
PMID: 26558346
Free PMC article.
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