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How activating mutations affect MEK1 regulation and function.
J Biol Chem. 2017 Nov 17;292(46):18814-18820. doi: 10.1074/jbc.C117.806067. Epub 2017 Oct 10.
J Biol Chem. 2017.
PMID: 29018093
Free PMC article.
Structure of the BRAF-MEK complex reveals a kinase activity independent role for BRAF in MAPK signaling.
Haling JR, Sudhamsu J, Yen I, Sideris S, Sandoval W, Phung W, Bravo BJ, Giannetti AM, Peck A, Masselot A, Morales T, Smith D, Brandhuber BJ, Hymowitz SG, Malek S.
Haling JR, et al.
Cancer Cell. 2014 Sep 8;26(3):402-413. doi: 10.1016/j.ccr.2014.07.007. Epub 2014 Aug 21.
Cancer Cell. 2014.
PMID: 25155755
Free article.
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