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Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J Biol Chem. 2020 Dec 4;295(49):16470-16486. doi: 10.1074/jbc.RA120.015444. Epub 2020 Oct 13.
J Biol Chem. 2020.
PMID: 33051202
Free PMC article.
Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP.
Vasilyev N, Polonskaia A, Darnell JC, Darnell RB, Patel DJ, Serganov A.
Vasilyev N, et al.
Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):E5391-400. doi: 10.1073/pnas.1515737112. Epub 2015 Sep 15.
Proc Natl Acad Sci U S A. 2015.
PMID: 26374839
Free PMC article.
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