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In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.
J Biol Chem. 2020 Dec 25;295(52):18316-18327. doi: 10.1074/jbc.RA120.016106. Epub 2020 Oct 27.
J Biol Chem. 2020.
PMID: 33109600
Free PMC article.
Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1.
Christensen EM, Patel SM, Korasick DA, Campbell AC, Krause KL, Becker DF, Tanner JJ.
Christensen EM, et al.
J Biol Chem. 2017 Apr 28;292(17):7233-7243. doi: 10.1074/jbc.M117.780288. Epub 2017 Mar 3.
J Biol Chem. 2017.
PMID: 28258219
Free PMC article.
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