PDB/5afm[Secondary Source ID] - Search Results

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An allosteric binding site of the α7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein.

Delbart F, Brams M, Gruss F, Noppen S, Peigneur S, Boland S, Chaltin P, Brandao-Neto J, von Delft F, Touw WG, Joosten RP, Liekens S, Tytgat J, Ulens C. Delbart F, et al. J Biol Chem. 2018 Feb 16;293(7):2534-2545. doi: 10.1074/jbc.M117.815316. Epub 2017 Dec 13. J Biol Chem. 2018. PMID: 29237730 Free PMC article.

A human-specific, truncated α7 nicotinic receptor subunit assembles with full-length α7 and forms functional receptors with different stoichiometries.

Lasala M, Corradi J, Bruzzone A, Esandi MDC, Bouzat C. Lasala M, et al. J Biol Chem. 2018 Jul 6;293(27):10707-10717. doi: 10.1074/jbc.RA117.001698. Epub 2018 May 21. J Biol Chem. 2018. PMID: 29784875 Free PMC article.

Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor.

Spurny R, Debaveye S, Farinha A, Veys K, Vos AM, Gossas T, Atack J, Bertrand S, Bertrand D, Danielson UH, Tresadern G, Ulens C. Spurny R, et al. Proc Natl Acad Sci U S A. 2015 May 12;112(19):E2543-52. doi: 10.1073/pnas.1418289112. Epub 2015 Apr 27. Proc Natl Acad Sci U S A. 2015. PMID: 25918415 Free PMC article.

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