PDB/5ta3[Secondary Source ID] - Search Results

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Ion-pulling simulations provide insights into the mechanisms of channel opening of the skeletal muscle ryanodine receptor.

Mowrey DD, Xu L, Mei Y, Pasek DA, Meissner G, Dokholyan NV. Mowrey DD, et al. J Biol Chem. 2017 Aug 4;292(31):12947-12958. doi: 10.1074/jbc.M116.760199. Epub 2017 Jun 5. J Biol Chem. 2017. PMID: 28584051 Free PMC article.

G4941K substitution in the pore-lining S6 helix of the skeletal muscle ryanodine receptor increases RyR1 sensitivity to cytosolic and luminal Ca².

Xu L, Mowrey DD, Chirasani VR, Wang Y, Pasek DA, Dokholyan NV, Meissner G. Xu L, et al. J Biol Chem. 2018 Feb 9;293(6):2015-2028. doi: 10.1074/jbc.M117.803247. Epub 2017 Dec 18. J Biol Chem. 2018. PMID: 29255089 Free PMC article.

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