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A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine.
J Gen Physiol. 2018 Nov 5;150(11):1554-1566. doi: 10.1085/jgp.201812124. Epub 2018 Oct 17.
J Gen Physiol. 2018.
PMID: 30333107
Free PMC article.
Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating.
Sierra-Valdez F, Azumaya CM, Romero LO, Nakagawa T, Cordero-Morales JF.
Sierra-Valdez F, et al.
J Biol Chem. 2018 Oct 12;293(41):16102-16114. doi: 10.1074/jbc.RA118.005066. Epub 2018 Aug 23.
J Biol Chem. 2018.
PMID: 30139744
Free PMC article.
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Cryo-EM structure of the cytoplasmic domain of murine transient receptor potential cation channel subfamily C member 6 (TRPC6).
Azumaya CM, Sierra-Valdez F, Cordero-Morales JF, Nakagawa T.
Azumaya CM, et al.
J Biol Chem. 2018 Jun 29;293(26):10381-10391. doi: 10.1074/jbc.RA118.003183. Epub 2018 May 11.
J Biol Chem. 2018.
PMID: 29752403
Free PMC article.
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