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Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection.
Lin J, Moradi E, Salenius K, Lehtipuro S, Häkkinen T, Laiho JE, Oikarinen S, Randelin S, Parikh HM, Krischer JP, Toppari J, Lernmark Å, Petrosino JF, Ajami NJ, She JX, Hagopian WA, Rewers MJ, Lloyd RE, Rautajoki KJ, Hyöty H, Nykter M; TEDDY Study Group. Lin J, et al. Among authors: parikh hm. Nat Commun. 2023 Nov 22;14(1):7630. doi: 10.1038/s41467-023-42763-9. Nat Commun. 2023. PMID: 37993433 Free PMC article.
Type 1 diabetes prediction in autoantibody-positive individuals: performance, time and money matter.
Ferrat LA, Templeman EL, Steck AK, Parikh HM, You L, Onengut-Gumuscu S, Gottlieb PA, Triolo TM, Rich SS, Krischer J, McQueen RB, Oram RA, Redondo MJ; Type 1 Diabetes TrialNet Study Group. Ferrat LA, et al. Among authors: parikh hm. Diabetologia. 2025 Aug;68(8):1709-1720. doi: 10.1007/s00125-025-06434-2. Epub 2025 May 10. Diabetologia. 2025. PMID: 40347237 Free PMC article.
Genetic Risk and Transition through Preclinical Stages of Type 1 Diabetes.
Steck AK, Parikh HM, Triolo TM, Ferrat L, You L, Gottlieb PA, Oram RA, Onengut-Gumuscu S, Krischer JP, Rich SS, Redondo MJ. Steck AK, et al. Among authors: parikh hm. J Clin Endocrinol Metab. 2025 Jul 9:dgaf392. doi: 10.1210/clinem/dgaf392. Online ahead of print. J Clin Endocrinol Metab. 2025. PMID: 40632818 Free PMC article.
Characteristics of autoantibody-positive individuals without high-risk HLA-DR4-DQ8 or HLA-DR3-DQ2 haplotypes.
Redondo MJ, Cuthbertson D, Steck AK, Herold KC, Oram R, Atkinson M, Brusko TM, Parikh HM, Krischer JP, Onengut-Gumuscu S, Rich SS, Sosenko JM; Type 1 Diabetes TrialNet Study Group. Redondo MJ, et al. Among authors: parikh hm. Diabetologia. 2025 Mar;68(3):588-601. doi: 10.1007/s00125-024-06338-7. Epub 2024 Dec 13. Diabetologia. 2025. PMID: 39670998 Free PMC article.
Race and Ethnicity, Socioeconomic Factors, and Epigenetic Age Acceleration in Survivors of Childhood Cancer.
Chen C, Plonski NM, Dong Q, Song N, Zhang X, Parikh HM, Finch ER, Easton J, Mulder HL, Walker E, Neale G, Pan Y, Li Q, Zhang J, Krull K, Robison LL, Armstrong GT, Yasui Y, Ness KK, Hudson MM, Wang H, Huang IC, Wang Z. Chen C, et al. Among authors: parikh hm. JAMA Netw Open. 2024 Jul 1;7(7):e2419771. doi: 10.1001/jamanetworkopen.2024.19771. JAMA Netw Open. 2024. PMID: 38954412 Free PMC article.
Progression to type 1 diabetes in the DPT-1 and TN07 clinical trials is critically associated with specific residues in HLA-DQA1-B1 heterodimers.
Zhao LP, Papadopoulos GK, Skyler JS, Pugliese A, Parikh HM, Kwok WW, Lybrand TP, Bondinas GP, Moustakas AK, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark Å. Zhao LP, et al. Among authors: parikh hm. Diabetologia. 2024 Nov;67(11):2481-2493. doi: 10.1007/s00125-024-06274-6. Epub 2024 Oct 1. Diabetologia. 2024. PMID: 39354095 Free PMC article.
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