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Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues.
Walker EM, Pearson GL, Lawlor N, Stendahl AM, Lietzke A, Sidarala V, Zhu J, Stromer T, Reck EC, Li J, Levi-D'Ancona E, Pasmooij MB, Hubers DL, Renberg A, Mohamed K, Parekh VS, Zhang IX, Thompson B, Zhang D, Ware SA, Haataja L, Qi N, Parker SCJ, Arvan P, Yin L, Kaufman BA, Satin LS, Sussel L, Stitzel ML, Soleimanpour SA. Walker EM, et al. Among authors: pasmooij mb. Science. 2025 Apr 11;388(6743):eadf2034. doi: 10.1126/science.adf2034. Epub 2025 Apr 11. Science. 2025. PMID: 39913641
LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes.
Li J, Deng Y, Gasser M, Zhu J, Walker EM, Sidarala V, Reck EC, Hubers DL, Pasmooij MB, Shin CS, Bandesh K, Motakis E, Nargund S, Kursawe R, Basrur V, Nesvizhskii AI, Stitzel ML, Chan DC, Rutter GA, Soleimanpour SA. Li J, et al. Among authors: pasmooij mb. Nat Metab. 2025 Aug;7(8):1570-1592. doi: 10.1038/s42255-025-01333-7. Epub 2025 Jul 21. Nat Metab. 2025. PMID: 40691304 Free PMC article.
TRAF6 integrates innate immune signals to regulate glucose homeostasis via Parkin-dependent and Parkin-independent mitophagy.
Levi-D'Ancona E, Walker EM, Zhu J, Deng Y, Sidarala V, Stendahl AM, Reck EC, Henry-Kanarek BA, Lietzke AC, Chai B, Pasmooij MB, Hubers DL, Basrur V, Ghosh S, Stiles L, Nesvizhskii AI, Shirihai OS, Soleimanpour SA. Levi-D'Ancona E, et al. Among authors: pasmooij mb. Sci Adv. 2025 Oct 10;11(41):eadw4153. doi: 10.1126/sciadv.adw4153. Epub 2025 Oct 8. Sci Adv. 2025. PMID: 41061082 Free PMC article.
TRAF6 integrates innate immune signals to regulate glucose homeostasis via Parkin-dependent and-independent mitophagy.
Levi-D'Ancona E, Walker EM, Zhu J, Deng Y, Sidarala V, Stendahl AM, Reck EC, Henry-Kanarek BA, Lietzke AC, Pasmooij MB, Hubers DL, Basrur V, Ghosh S, Stiles L, Nesvizhskii AI, Shirihai OS, Soleimanpour SA. Levi-D'Ancona E, et al. Among authors: pasmooij mb. bioRxiv [Preprint]. 2025 Sep 5:2025.01.31.635900. doi: 10.1101/2025.01.31.635900. bioRxiv. 2025. Update in: Sci Adv. 2025 Oct 10;11(41):eadw4153. doi: 10.1126/sciadv.adw4153. PMID: 39974969 Free PMC article. Updated. Preprint.
LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes.
Li J, Zhu J, Deng Y, Reck EC, Walker EM, Sidarala V, Hubers DL, Pasmooij MB, Shin CS, Bandesh K, Motakis E, Nargund S, Kursawe R, Basrur V, Nesvizhskii AI, Stitzel ML, Chan DC, Soleimanpour SA. Li J, et al. Among authors: pasmooij mb. bioRxiv [Preprint]. 2024 Jun 3:2024.06.03.597215. doi: 10.1101/2024.06.03.597215. bioRxiv. 2024. Update in: Nat Metab. 2025 Aug;7(8):1570-1592. doi: 10.1038/s42255-025-01333-7. PMID: 38895283 Free PMC article. Updated. Preprint.