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Ondansetron has similar clinical efficacy against both nausea and vomiting.
Jokela RM, Cakmakkaya OS, Danzeisen O, Korttila KT, Kranke P, Malhotra A, Paura A, Radke OC, Sessler DI, Soikkeli A, Roewer N, Apfel CC. Jokela RM, et al. Among authors: paura a. Anaesthesia. 2009 Feb;64(2):147-51. doi: 10.1111/j.1365-2044.2008.05732.x. Anaesthesia. 2009. PMID: 19143691 Free article. Clinical Trial.
[A factorial trial of six interventions for the prevention of postoperative nausea and vomiting].
Apfel CC, Bacher A, Biedler A, Danner K, Danzeisen O, Eberhart LH, Forst H, Fritz G, Hergert M, Frings G, Goebel A, Hopf HB, Kerger H, Kranke P, Lange M, Mertzlufft F, Motsch J, Paura A, Roewer N, Schneider E, Stoecklein K, Wermelt J, Zernak C. Apfel CC, et al. Among authors: paura a. Anaesthesist. 2005 Mar;54(3):201-9. doi: 10.1007/s00101-005-0803-8. Anaesthesist. 2005. PMID: 15731931 Clinical Trial. German.