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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1918 1
1946 1
1947 1
1948 1
1951 1
1953 1
1954 1
1955 1
1956 4
1957 2
1958 1
1959 1
1960 4
1961 2
1962 2
1963 2
1964 1
1965 3
1966 6
1967 4
1968 2
1969 3
1970 3
1971 6
1972 4
1973 4
1974 11
1975 5
1976 9
1977 15
1978 2
1979 7
1980 4
1981 12
1982 5
1983 8
1984 13
1985 14
1986 9
1987 8
1988 10
1989 9
1990 20
1991 23
1992 19
1993 26
1994 18
1995 28
1996 23
1997 14
1998 16
1999 22
2000 23
2001 23
2002 33
2003 21
2004 30
2005 30
2006 37
2007 35
2008 38
2009 46
2010 36
2011 46
2012 56
2013 57
2014 50
2015 67
2016 74
2017 69
2018 72
2019 81
2020 88
2021 82
2022 64
2023 77
2024 70
2025 56

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1,609 results

Results by year

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Page 1
Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity.
Zhang T, Yu W, Cheng X, Yeung J, Ahumada V, Norris PC, Pearson MJ, Yang X, van Deursen W, Halcovich C, Nassar A, Vesely MD, Zhang Y, Zhang JP, Ji L, Flies DB, Liu L, Langermann S, LaRochelle WJ, Humphrey R, Zhao D, Zhang Q, Zhang J, Gu R, Schalper KA, Sanmamed MF, Chen L. Zhang T, et al. Among authors: pearson mj. Sci Immunol. 2024 Apr 26;9(94):eadh2334. doi: 10.1126/sciimmunol.adh2334. Epub 2024 Apr 26. Sci Immunol. 2024. PMID: 38669316
Drugging an undruggable pocket on KRAS.
Kessler D, Gmachl M, Mantoulidis A, Martin LJ, Zoephel A, Mayer M, Gollner A, Covini D, Fischer S, Gerstberger T, Gmaschitz T, Goodwin C, Greb P, Häring D, Hela W, Hoffmann J, Karolyi-Oezguer J, Knesl P, Kornigg S, Koegl M, Kousek R, Lamarre L, Moser F, Munico-Martinez S, Peinsipp C, Phan J, Rinnenthal J, Sai J, Salamon C, Scherbantin Y, Schipany K, Schnitzer R, Schrenk A, Sharps B, Siszler G, Sun Q, Waterson A, Wolkerstorfer B, Zeeb M, Pearson M, Fesik SW, McConnell DB. Kessler D, et al. Among authors: pearson m. Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):15823-15829. doi: 10.1073/pnas.1904529116. Epub 2019 Jul 22. Proc Natl Acad Sci U S A. 2019. PMID: 31332011 Free PMC article.
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis.
Chaurasia B, Tippetts TS, Mayoral Monibas R, Liu J, Li Y, Wang L, Wilkerson JL, Sweeney CR, Pereira RF, Sumida DH, Maschek JA, Cox JE, Kaddai V, Lancaster GI, Siddique MM, Poss A, Pearson M, Satapati S, Zhou H, McLaren DG, Previs SF, Chen Y, Qian Y, Petrov A, Wu M, Shen X, Yao J, Nunes CN, Howard AD, Wang L, Erion MD, Rutter J, Holland WL, Kelley DE, Summers SA. Chaurasia B, et al. Among authors: pearson m. Science. 2019 Jul 26;365(6451):386-392. doi: 10.1126/science.aav3722. Epub 2019 Jul 4. Science. 2019. PMID: 31273070 Free PMC article.
Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling.
Wilding B, Scharn D, Böse D, Baum A, Santoro V, Chetta P, Schnitzer R, Botesteanu DA, Reiser C, Kornigg S, Knesl P, Hörmann A, Köferle A, Corcokovic M, Lieb S, Scholz G, Bruchhaus J, Spina M, Balla J, Peric-Simov B, Zimmer J, Mitzner S, Fett TN, Beran A, Lamarre L, Gerstberger T, Gerlach D, Bauer M, Bergner A, Schlattl A, Bader G, Treu M, Engelhardt H, Zahn S, Fuchs JE, Zuber J, Ettmayer P, Pearson M, Petronczki M, Kraut N, McConnell DB, Solca F, Neumüller RA. Wilding B, et al. Among authors: pearson m. Nat Cancer. 2022 Jul;3(7):821-836. doi: 10.1038/s43018-022-00412-y. Epub 2022 Jul 26. Nat Cancer. 2022. PMID: 35883003
BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition.
Hofmann MH, Gmachl M, Ramharter J, Savarese F, Gerlach D, Marszalek JR, Sanderson MP, Kessler D, Trapani F, Arnhof H, Rumpel K, Botesteanu DA, Ettmayer P, Gerstberger T, Kofink C, Wunberg T, Zoephel A, Fu SC, Teh JL, Böttcher J, Pototschnig N, Schachinger F, Schipany K, Lieb S, Vellano CP, O'Connell JC, Mendes RL, Moll J, Petronczki M, Heffernan TP, Pearson M, McConnell DB, Kraut N. Hofmann MH, et al. Among authors: pearson m. Cancer Discov. 2021 Jan;11(1):142-157. doi: 10.1158/2159-8290.CD-20-0142. Epub 2020 Aug 19. Cancer Discov. 2021. PMID: 32816843 Free PMC article.
National stroke audit.
Rudd AG, Pearson M. Rudd AG, et al. Among authors: pearson m. Clin Med (Lond). 2002 Nov-Dec;2(6):496-8. doi: 10.7861/clinmedicine.2-6-496. Clin Med (Lond). 2002. PMID: 12528958 Free PMC article. No abstract available.
Deconstructing PML-induced premature senescence.
Bischof O, Kirsh O, Pearson M, Itahana K, Pelicci PG, Dejean A. Bischof O, et al. Among authors: pearson m. EMBO J. 2022 Sep 1;41(17):e112081. doi: 10.15252/embj.2022112081. EMBO J. 2022. PMID: 36047049 Free PMC article.
Viruses of botrytis.
Pearson MN, Bailey AM. Pearson MN, et al. Adv Virus Res. 2013;86:249-72. doi: 10.1016/B978-0-12-394315-6.00009-X. Adv Virus Res. 2013. PMID: 23498909 Review.
1,609 results