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65 results

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Page 1
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Behan FM, Iorio F, Picco G, Gonçalves E, Beaver CM, Migliardi G, Santos R, Rao Y, Sassi F, Pinnelli M, Ansari R, Harper S, Jackson DA, McRae R, Pooley R, Wilkinson P, van der Meer D, Dow D, Buser-Doepner C, Bertotti A, Trusolino L, Stronach EA, Saez-Rodriguez J, Yusa K, Garnett MJ. Behan FM, et al. Among authors: picco g. Nature. 2019 Apr;568(7753):511-516. doi: 10.1038/s41586-019-1103-9. Epub 2019 Apr 10. Nature. 2019. PMID: 30971826 Free article.
Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells.
Picco G, Rao Y, Al Saedi A, Lee Y, Vieira SF, Bhosle S, May K, Herranz-Ors C, Walker SJ, Shenje R, Dincer C, Gibson F, Banerjee R, Hewitson Z, Werner T, Cottom JE, Peng Y, Deng N, Zhang Y, Nartey EN, Nickels L, Landis P, Conticelli D, McCarten K, Bush J, Sharma M, Lightfoot H, House D, Milford E, Grant EK, Glogowski MP, Wagner CD, Bantscheff M, Rutkowska-Klute A; Cell Model Network UK Group; Zappacosta F, Pettinger J, Barthorpe S, Eberl HC, Jones BT, Schneck JL, Murphy DJ, Voest EE, Taygerly JP, DeMartino MP, Coelho MA, Houseley J, Sharma G, Schwartz B, Garnett MJ. Picco G, et al. Cancer Discov. 2024 Aug 2;14(8):1457-1475. doi: 10.1158/2159-8290.CD-24-0052. Cancer Discov. 2024. PMID: 38587317 Free PMC article.
Base editing screens map mutations affecting interferon-γ signaling in cancer.
Coelho MA, Cooper S, Strauss ME, Karakoc E, Bhosle S, Gonçalves E, Picco G, Burgold T, Cattaneo CM, Veninga V, Consonni S, Dinçer C, Vieira SF, Gibson F, Barthorpe S, Hardy C, Rein J, Thomas M, Marioni J, Voest EE, Bassett A, Garnett MJ. Coelho MA, et al. Among authors: picco g. Cancer Cell. 2023 Feb 13;41(2):288-303.e6. doi: 10.1016/j.ccell.2022.12.009. Epub 2023 Jan 19. Cancer Cell. 2023. PMID: 36669486 Free PMC article.
Base editing screens define the genetic landscape of cancer drug resistance mechanisms.
Coelho MA, Strauss ME, Watterson A, Cooper S, Bhosle S, Illuzzi G, Karakoc E, Dinçer C, Vieira SF, Sharma M, Moullet M, Conticelli D, Koeppel J, McCarten K, Cattaneo CM, Veninga V, Picco G, Parts L, Forment JV, Voest EE, Marioni JC, Bassett A, Garnett MJ. Coelho MA, et al. Among authors: picco g. Nat Genet. 2024 Nov;56(11):2479-2492. doi: 10.1038/s41588-024-01948-8. Epub 2024 Oct 18. Nat Genet. 2024. PMID: 39424923 Free PMC article.
Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair-Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy.
Picco G, Cattaneo CM, van Vliet EJ, Crisafulli G, Rospo G, Consonni S, Vieira SF, Rodríguez IS, Cancelliere C, Banerjee R, Schipper LJ, Oddo D, Dijkstra KK, Cinatl J, Michaelis M, Yang F, Di Nicolantonio F, Sartore-Bianchi A, Siena S, Arena S, Voest EE, Bardelli A, Garnett MJ; Cell Model Network UK Group. Picco G, et al. Cancer Discov. 2021 Aug;11(8):1923-1937. doi: 10.1158/2159-8290.CD-20-1508. Epub 2021 Apr 9. Cancer Discov. 2021. PMID: 33837064 Free article.
Minimal genome-wide human CRISPR-Cas9 library.
Gonçalves E, Thomas M, Behan FM, Picco G, Pacini C, Allen F, Vinceti A, Sharma M, Jackson DA, Price S, Beaver CM, Dovey O, Parry-Smith D, Iorio F, Parts L, Yusa K, Garnett MJ. Gonçalves E, et al. Among authors: picco g. Genome Biol. 2021 Jan 21;22(1):40. doi: 10.1186/s13059-021-02268-4. Genome Biol. 2021. PMID: 33478580 Free PMC article.
Cardiac troponin I in asphyxiated neonates.
Trevisanuto D, Picco G, Golin R, Doglioni N, Altinier S, Zaninotto M, Zanardo V. Trevisanuto D, et al. Among authors: picco g. Biol Neonate. 2006;89(3):190-3. doi: 10.1159/000089795. Epub 2005 Nov 17. Biol Neonate. 2006. PMID: 16293961
65 results