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3,962 results

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Page 1
PINA 3.0: mining cancer interactome.
Du Y, Cai M, Xing X, Ji J, Yang E, Wu J. Du Y, et al. Nucleic Acids Res. 2021 Jan 8;49(D1):D1351-D1357. doi: 10.1093/nar/gkaa1075. Nucleic Acids Res. 2021. PMID: 33231689 Free PMC article.
Therefore, we update the Protein Interaction Network Analysis (PINA) platform to version 3.0, to integrate the unified human interactome with RNA-seq transcriptomes and mass spectrometry-based proteomes across tens of cancer types. ...Furthermore, a brand-new web interface …
Therefore, we update the Protein Interaction Network Analysis (PINA) platform to version 3.0, to integrate the unified human interact …
Polatuzumab vedotin or pinatuzumab vedotin plus rituximab in patients with relapsed or refractory non-Hodgkin lymphoma: final results from a phase 2 randomised study (ROMULUS).
Morschhauser F, Flinn IW, Advani R, Sehn LH, Diefenbach C, Kolibaba K, Press OW, Salles G, Tilly H, Chen AI, Assouline S, Cheson BD, Dreyling M, Hagenbeek A, Zinzani PL, Jones S, Cheng J, Lu D, Penuel E, Hirata J, Wenger M, Chu YW, Sharman J. Morschhauser F, et al. Lancet Haematol. 2019 May;6(5):e254-e265. doi: 10.1016/S2352-3026(19)30026-2. Epub 2019 Mar 29. Lancet Haematol. 2019. PMID: 30935953 Clinical Trial.
BACKGROUND: Antibody-drug conjugates (ADCs) polatuzumab vedotin (pola) and pinatuzumab vedotin (pina) showed clinical activity and tolerability in phase 1 trials. The aim of this multicentre, open-label, phase 2 study was to compare rituximab plus pola (R-pola) or pina
BACKGROUND: Antibody-drug conjugates (ADCs) polatuzumab vedotin (pola) and pinatuzumab vedotin (pina) showed clinical activity and to …
PINA v2.0: mining interactome modules.
Cowley MJ, Pinese M, Kassahn KS, Waddell N, Pearson JV, Grimmond SM, Biankin AV, Hautaniemi S, Wu J. Cowley MJ, et al. Nucleic Acids Res. 2012 Jan;40(Database issue):D862-5. doi: 10.1093/nar/gkr967. Epub 2011 Nov 8. Nucleic Acids Res. 2012. PMID: 22067443 Free PMC article.
The Protein Interaction Network Analysis (PINA) platform is a comprehensive web resource, which includes a database of unified protein-protein interaction data integrated from six manually curated public databases, and a set of built-in tools for network construction, filt …
The Protein Interaction Network Analysis (PINA) platform is a comprehensive web resource, which includes a database of unified protei …
Leptomeningeal Disease.
Piña Y, Gramatzki D, Forsyth P, Lee EQ, Le Rhun E. Piña Y, et al. Hematol Oncol Clin North Am. 2022 Feb;36(1):189-215. doi: 10.1016/j.hoc.2021.08.009. Epub 2021 Oct 29. Hematol Oncol Clin North Am. 2022. PMID: 34756800 Review. No abstract available.
Comment on Pina et al. Ten Approaches That Improve Immunostaining: A Review of the Latest Advances for the Optimization of Immunofluorescence. Int. J. Mol. Sci. 2022, 23, 1426.
Sheval EV. Sheval EV. Int J Mol Sci. 2022 Apr 15;23(8):4372. doi: 10.3390/ijms23084372. Int J Mol Sci. 2022. PMID: 35457190 Free PMC article.
With great interest, I have read the article "Ten Approaches That Improve Immunostaining: A Review of the Latest Advances for the Optimization of Immunofluorescence" written by Pina et al. [...]....
With great interest, I have read the article "Ten Approaches That Improve Immunostaining: A Review of the Latest Advances for the Optimizati …
PinA inhibits ATP hydrolysis and energy-dependent protein degradation by Lon protease.
Hilliard JJ, Simon LD, Van Melderen L, Maurizi MR. Hilliard JJ, et al. J Biol Chem. 1998 Jan 2;273(1):524-7. doi: 10.1074/jbc.273.1.524. J Biol Chem. 1998. PMID: 9417111 Free article.
Thus, PinA does not block the proteolytic active site or the allosteric protein-binding site on Lon. ...Inhibition was noncompetitive with respect to ATP. PinA did not block activation of peptide cleavage by nonhydrolyzable analogs of ATP. These data suggest that …
Thus, PinA does not block the proteolytic active site or the allosteric protein-binding site on Lon. ...Inhibition was noncompetitive …
A cornichon protein controls polar localization of the PINA auxin transporter in Physcomitrium patens.
Yáñez-Domínguez C, Lagunas-Gómez D, Torres-Cifuentes DM, Bezanilla M, Pantoja O. Yáñez-Domínguez C, et al. Development. 2023 May 1;150(9):dev201635. doi: 10.1242/dev.201635. Epub 2023 May 5. Development. 2023. PMID: 37052186 Free PMC article.
Mutant analyses revealed that cornichon genes regulate different growth processes during the moss life cycle by controlling auxin transport, with CNIH2 functioning as a specific cargo receptor for the auxin efflux carrier PINA, with the C terminus of the receptor regulatin …
Mutant analyses revealed that cornichon genes regulate different growth processes during the moss life cycle by controlling auxin transport, …
PINA is essential for growth and positively influences NIMA function in Aspergillus nidulans.
Joseph JD, Daigle SN, Means AR. Joseph JD, et al. J Biol Chem. 2004 Jul 30;279(31):32373-84. doi: 10.1074/jbc.M405415200. Epub 2004 Jun 3. J Biol Chem. 2004. PMID: 15178679 Free article.
Here we explore the physiological roles of the Pin1 orthologue, PINA, in A. nidulans and evaluate the relevance of the interaction of PINA with NIMA in this fungus. We find pinA to be an essential gene in A. nidulans. In addition, when PINA levels are …
Here we explore the physiological roles of the Pin1 orthologue, PINA, in A. nidulans and evaluate the relevance of the interaction of …
A new strain of rat for functional analysis of PINA.
Ahmed S, Deng J, Borjigin J. Ahmed S, et al. Brain Res Mol Brain Res. 2005 Jun 13;137(1-2):63-9. doi: 10.1016/j.molbrainres.2005.02.025. Epub 2005 Mar 31. Brain Res Mol Brain Res. 2005. PMID: 15950762
Previously, we have demonstrated presence of an alternative product termed PIneal Night-specific ATPase (PINA) generated by an intronic promoter in Atp7b gene. Analysis of LEC rat in this study demonstrates that PINA is absent in the LEC pineal establishing its usef …
Previously, we have demonstrated presence of an alternative product termed PIneal Night-specific ATPase (PINA) generated by an intron …
3,962 results