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48 results

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Page 1
Expanded profiling of Remdesivir as a broad-spectrum antiviral and low potential for interaction with other medications in vitro.
Radoshitzky SR, Iversen P, Lu X, Zou J, Kaptein SJF, Stuthman KS, Van Tongeren SA, Steffens J, Gong R, Truong H, Sapre AA, Yang H, Xie X, Chia JJ, Song ZJ, Leventhal SM, Chan J, Shornikov A, Zhang X, Cowfer D, Yu H, Warren T, Cihlar T, Porter DP, Neyts J, Shi PY, Wells J, Bilello JP, Feng JY. Radoshitzky SR, et al. Among authors: porter dp. Sci Rep. 2023 Feb 23;13(1):3131. doi: 10.1038/s41598-023-29517-9. Sci Rep. 2023. PMID: 36823196 Free PMC article.
Oral administration of obeldesivir protects nonhuman primates against Sudan ebolavirus.
Cross RW, Woolsey C, Chu VC, Babusis D, Bannister R, Vermillion MS, Geleziunas R, Barrett KT, Bunyan E, Nguyen AQ, Cihlar T, Porter DP, Prasad AN, Deer DJ, Borisevich V, Agans KN, Martinez J, Harrison MB, Dobias NS, Fenton KA, Bilello JP, Geisbert TW. Cross RW, et al. Among authors: porter dp. Science. 2024 Mar 15;383(6688):eadk6176. doi: 10.1126/science.adk6176. Epub 2024 Mar 15. Science. 2024. PMID: 38484056
Remdesivir postexposure prophylaxis limits measles-induced "immune amnesia" and measles antibody responses in macaques.
Chan AKP, Liu L, Morgenlander WR, Thakar M, Peart Akindele NA, Brockhurst J, Ghimire S, Bartlett ML, Metcalf Pate KA, Chu VC, Vermillion MS, Porter DP, Cihlar T, Mina MJ, Larman HB, Griffin DE. Chan AKP, et al. Among authors: porter dp. JCI Insight. 2025 Apr 22;10(11):e190740. doi: 10.1172/jci.insight.190740. eCollection 2025 Jun 9. JCI Insight. 2025. PMID: 40306326 Free PMC article.
SARS-CoV-2 resistance analyses from the Phase 3 PINETREE study of remdesivir treatment in nonhospitalized participants.
Rodriguez L, Lee HW, Li J, Martin R, Han D, Xu S, Moshiri J, Peinovich N, Camus G, Perry JK, Hyland RH, Porter DP, Abdelghany M, Götte M, Hedskog C. Rodriguez L, et al. Among authors: porter dp. Antimicrob Agents Chemother. 2025 Feb 13;69(2):e0123824. doi: 10.1128/aac.01238-24. Epub 2024 Dec 19. Antimicrob Agents Chemother. 2025. PMID: 39699245 Free PMC article. Clinical Trial.
Subcutaneous remdesivir administration prevents interstitial pneumonia in rhesus macaques inoculated with SARS-CoV-2.
Williamson BN, Pérez-Pérez L, Schwarz B, Feldmann F, Holbrook MG, Singh M, Lye DS, Babusis D, Subramanian R, Haddock E, Okumura A, Hanley PW, Lovaglio J, Bosio CM, Porter DP, Cihlar T, Mackman RL, Saturday G, de Wit E. Williamson BN, et al. Among authors: porter dp. Antiviral Res. 2022 Feb;198:105246. doi: 10.1016/j.antiviral.2022.105246. Epub 2022 Jan 13. Antiviral Res. 2022. PMID: 35032523 Free PMC article.
Remdesivir efficacy against yellow fever in a hamster model.
Julander JG, Bunyan E, Jordan R, Porter DP. Julander JG, et al. Among authors: porter dp. Antiviral Res. 2022 Jul;203:105331. doi: 10.1016/j.antiviral.2022.105331. Epub 2022 May 6. Antiviral Res. 2022. PMID: 35533777
48 results